The Gri-fill System 3.0 from Grifols USA is a closed-system automated compounding device that automatically reconstitutes solutions and withdraws volumes in a completely controlled system to help enhance sterility. The device draws up the exact dose and pushes it into specialized bags with pre-attached 0.22-micron filters in the filling ports. The system uses a terminal sterilization process to filter each dose and then tests and documents the integrity of each filter to enhance the compound\'s sterility. Gri-Fill reduces waste and extends the beyond-use-date of compounded medicines. Whereas single-dose vials must be used within six hours after opening, the system enables pharmacy to save the remainder of the vial in its filtered bags, allowing for potential use of costly drugs the following day.
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