The Pyxis Mini system is a smaller automated dispensing cabinet (ADC) solution for securely managing the limited medication inventories required in alternate care locations. Part of the Pyxis ES system, the Pyxis Mini extends medication management to ancillary care settings. Accessed by a USB-connected PC or laptop, the system uses secure CUBIE pockets for medication storage and single line-item access. Used in conjunction with the smart CUBIE system, this supports secure, closed-loop transportation of filled and checked CUBIE pockets from a central pharmacy to decentralized locations, supporting medication safety, cost management, and efficient clinical workflows.