HD Spills

December 2021 : USP 800 - Vol.18 No. 12 - Page #4
Category: USP Training Programs

Because the risk of exposure from an HD spill can be significant, facilities must mitigate this risk via the development of thorough P&Ps and the creation of effective and easily accessible spill kits. Key to this effort is effective and continuous training.

It is highly recommended that drills be conducted regularly in all high-risk areas by pouring talcum powder or liquid Tylenol on the floor and announcing a spill. The resulting response should be reviewed for expediency, regulatory compliance, and adherence to P&Ps.


Most facilities rely on commercially available HD spill kits. Just 22% are purchasing commercially available kits and then supplementing them with additional supplies, such as gloves and gowns in a range of sizes. Notably, it is the smallest facilities that are most likely to customize their off-the-shelf kits.


The number of facilities conducting simulated HD spill drills continues to improve; nevertheless, this remains a minority practice outside of pharmacy.


Following an HD spill in an engineering control, PeridoxRTU, Surface Safe, and HDClean are the most commonly utilized agents for decontamination.

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