Sterile compounding teams routinely navigate the rigor of USP standards to create and execute on workflows for garbing, aseptic technique, environmental monitoring (EM), cleaning and disinfection, and documentation.1 However, beyond these core standards, best practices around the use of incubators can often go overlooked. Incubators play an important role in processing EM samples and personnel... Read more
Once a finished chemotherapy preparation leaves the hazardous buffer room, a variety of staff members, including pharmacists, delivery staff, nursing, and environmental services, may touch the preparation during its lifecycle. The safe handling practices conducted within the containment primary engineering control (C-PEC) are as critical for the compounder’s protection as they are for... Read more
Sterile compounding relies on clean, controlled, and orderly cleanroom environments, making aseptic technique foundational to this work. However, hazardous drug (HD) spills remain an unavoidable reality in pharmacy practice. A vial may slip from gloved hands during preparation, fall while being transported to the biological safety cabinet (BSC), or break during restocking. Such events pose exposure... Read more
Given USP’s requirement that entities compounding sterile preparations execute a monitoring program to proactively minimize the risk of compounded sterile preparation (CSP) contamination, the goal of a microbiological air and surface monitoring program is to inform the state of control in the compounding area. When executed thoughtfully, the program can further serve to generate data that can... Read more
Q&A with Katheleen Kane, PharmD, MBA, BCSCP, DPLAAssistant Director of Pharmacy, Compounding Integrity and Compounding Regulatory Compliance UChicago Medicine Health
Pharmacy Purchasing & Products: Why is it important to have standardized P&Ps for CSTD use?
Kathleen Kane, PharmD, MBA, BCSCP, DPLA: Operating without standardized policies and procedures (P&Ps)... Read more
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