Simplex Isolation Systems offers a new white paper that explores the challenges imposed by USP <800> Section 5: Facilities and Engineering Controls. Developed to help health care institutions understand the necessary upgrades and modifications required to achieve compliance, the paper provides ways organizations can leverage their current facility layout and infrastructure to keep modifications within budget. Considerations on Facility and Engineering Controls in the Wake of USP <800> covers space configurations for receipt, unpacking, storage, and compounding of hazardous drugs; optimal space layouts for nonsterile and sterile hazardous drug compounding rooms; modular versus traditional stick-built secondary engineering control rooms; and typical challenges and potential solutions recommended for compliance. The white paper is available online for download.