WM PharmEcology publicizes the newly revised 10-Step Blueprint for Managing Pharmaceutical Waste in US Healthcare Facilities, released by the EPA. Initially released in 2006 and updated in 2008, the 2022 version features the Subpart P Hazardous Waste Pharmaceuticals Rule, the hazardous waste Sewer Ban, and the OTC Nicotine Exemption. The revision provides the Quick Start Guide, a step-by-step guide to notifying under Subpart P, and a more comprehensive 10 step approach to implementing or revising a hazardous waste pharmaceutical program. The blueprint can be accessed online at the EPA’s website or at the Healthcare Environmental Resource Center.