Thio from Thiopoly is an Internet of Things (IoT)-based solution designed to address challenges of drug distribution, logistics, and inventory management in ambulatory, outpatient, and clinic settings. The onboard sensing can facilitate frictionless grab-and-go workflows, and the wireless cellular capability enables secure, direct communication with the cloud. Thio requires no tagging, no training, and no health system IT resources. The system can be deployed in a variety of settings, including refrigerated environments, and integrates inventory analytics with environmental controls, geolocation, diversion monitoring, and simulation capabilities to enable more advanced automation. Designed to be cost effective and scalable, Thio aims to free capital, unburden IT, reduce waste, and increase pharmacy productivity.